Human Growth Hormone (HGH)
1. What is it and where does it come
from?
Growth Hormone, a polypeptide hormone secreted by the anterior pituitary
gland that regulates tissue growth, cellular repair, energy levels, fat
loss, and muscle growth, is the latest advance in bodybuilding
supplementation! Growth Hormone (GH) is the master hormone, because it is
released by the master gland--the anterior pituitary gland. While GH is not
necessary or critical to one's survival, it seems to play an important
evolutionary role in human development.
During puberty, GH levels dictate a person's height and bone size. After
puberty, GH continues to regulate the body's metabolism. High Quality Growth
Hormone Supplements are available from Bodybuilding.com!
2. What does it do and what scientific
studies give evidence to support this?
Human Growth Hormone levels decline rapidly after age 30. These HGH levels,
along with the related IGF-1 amounts, must be elevated in order to maximize
muscular size and growth. Human Growth Hormone levels are associated with
decreased fat, increased muscle mass, high energy, and increased sex drive.
It is HGH that has been found in studies to facilitate the metabolism of
fats in the body. HGH is also known for it’s powerful muscle-building
effects. Awesome! Increasing HGH is definitely a good thing, especially for
bodybuilders. HGH tends to decrease naturally with age, so the older you
get, the harder it is to lose fat.
Metabolically speaking, GH is responsible for the regulation of insulin
(glucose metabolism), protein synthesis, transportation of amino acids
across cell membranes, growth factor-1, a metabolic liver hormone) and
IGF-2, osteablast production (bone mass) and fat metabolism. GH also has a
profound effect on the immune system.
During fetal brain development, GH works closely to stimulate IGF-2
production--known to be one of the primary hormones responsible for
cognitive development and IQ in children. IGF-2 is the growth factor which
stimulates brain cell growth and development.
Between the ages of 20 and 25, GH production begins a steady decline, and
research associates this correspondence with the phenomena we call aging.
Somatopause (Soma = GH) is the term used to describe this condition. The
human brain shrinks in size by as much as 30% by the time we die, as do
other vital organs. Much of this is due to the dramatic drop in the
production of somatomedins (growth factors) with age, which in turn are
regulated by GH. Within the psychological domain, when GH levels drop, mood
levels become less stable and the feelings of youthful resilience ( the
ability to "bounce back") diminishes.
GH is one of the most extensively researched hormones in the body.
Anti-aging specialists focus on its ability to regenerate kidney, lung,
heart, and liver tissue.
The majority of GH research has focused on its clinical application at
injectable dosage levels (from 1 to 2 I.U.s). However, research is now
surfacing regarding the effects of micro-dilution supplementation on quality
of life.
Until 1996, GH was cost-prohibitive for the average American, available
in injectable form only. Fortunately, in 1996, due to the development of
advanced delivery systems, Americans were presented with other viable
options, oral spray micro-dilution supplementation, and cap/tab
supplementation.
3. Therapeutic Effects: Effective Use of HGH in Bodybuilding
Human Growth Hormone (HGH) has been extensively studied both clinically and
theoreticaly for many decades. GH has been referred to as the "Fountain of
Youth". It has astounded the medical community with its numerous positive
physiological effects on degenerative conditions related to both aging and
disease. The reported higher energy levels, enhanced libido and sexual
performance; regrowth of internal organs that shrink with age; and greater
cardiac output. In addition, superior immune function, better kidney
function, lowering of blood pressure, and improved cholesterol profile
(higher HDL and lower LDL) have been documented. Younger thicker skin with
tightening and lessening of wrinkles, hair growth, sharper vision, mood
elevation/releif from depression, increased memery retention, improved
sleep, decreased recovery time from exercise, muscle strain/injury, and
regeneration of tissues in degenerative diseases have also been noted.
4. Pharmacology:
HGH supplementation works on the hypothalmic-pituitary axis and follows the
natural sequence of GH production by stimulating the hypothalamus to produce
GHRH, which in turn stimulates the anterior pituitary to release
Somatotropin. Revostatin is a Somatostatin suppressant. Somatostatin is the
antagonistic hormone that blocks growth hormone production when blood levels
of Somatotropin and IGF-1 rise.
5. Indications:
For reversal of the aging process (see Therapeutic Effects), and as an aid
to both male and female athletes seeking to safely increase their natural GH
production.
6. Precautions:
HGH should not be administered to persons who have not completed their long
bone growth i.e.; children or adolescents, without first consulting a health
care professional familiar with HGH therapy. In general, HGH supplementation
is reserved for individuals over age 20.
8. Side Effects:
No adverse side effects have been reported when used as directed. Follow the
directions and recommendations per individual supplement.
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